Francis C Colpaert Selected Research

5-HT1A Serotonin Receptor

7/2007	Curative-like analgesia in a neuropathic pain model: parametric analysis of the dose and the duration of treatment with a high-efficacy 5-HT(1A) receptor agonist.
2/2006	High-efficacy 5-hydroxytryptamine 1A receptor activation counteracts opioid hyperallodynia and affective conditioning.
1/2006	5-HT(1A) receptor activation: new molecular and neuroadaptive mechanisms of pain relief.
10/2005	The novel analgesic, F 13640, produces intra- and postoperative analgesia in a rat model of surgical pain.
12/2004	Effects of the combined continuous administration of morphine and the high-efficacy 5-HT1A agonist, F 13640 in a rat model of trigeminal neuropathic pain.
8/2004	High-efficacy 5-HT1A receptor activation causes a curative-like action on allodynia in rats with spinal cord injury.
6/2004	Role of spinal 5-HT(1A) receptors in morphine analgesia and tolerance in rats.
10/2003	The very-high-efficacy 5-HT1A receptor agonist, F 13640, preempts the development of allodynia-like behaviors in rats with spinal cord injury.
12/2002	The 5-HT(1A) receptor agonist F 13640 attenuates mechanical allodynia in a rat model of trigeminal neuropathic pain.
10/2002	5-HT1A receptor activation and anti-cataleptic effects: high-efficacy agonists maximally inhibit haloperidol-induced catalepsy.

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Francis C Colpaert Research Topics

Disease

9	Hyperalgesia 07/2007 - 12/2002
9	Pain (Aches) 02/2006 - 04/2003
6	Neuralgia (Stump Neuralgia) 07/2007 - 12/2002
2	Memory Disorders (Memory Loss) 09/2010 - 04/2002
2	Spinal Cord Injuries (Spinal Cord Injury) 08/2004 - 10/2003
2	Trigeminal Neuralgia (Tic Douloureux) 08/2003 - 12/2002
1	Chronic Pain 07/2007
1	Opioid-Related Disorders (Opiate Addiction) 02/2006
1	Nociceptive Pain 01/2006
1	Postoperative Pain 10/2005
1	Inflammation (Inflammations) 04/2004
1	Contracture 01/2004
1	Headache (Headaches) 05/2003
1	Catalepsy 10/2002
1	Alzheimer Disease (Alzheimer's Disease) 04/2002

Drug/Important Bio-Agent (IBA)

10	befiradolIBA 07/2007 - 12/2002
10	5-HT1A Serotonin ReceptorIBA 07/2007 - 10/2002
6	Analgesics (Analgesic Drugs)IBA 07/2007 - 04/2003
5	Morphine (MS Contin)FDA LinkGeneric 02/2006 - 04/2003
4	Opioid Analgesics (Opioids)IBA 07/2007 - 10/2005
3	Serotonin (5 Hydroxytryptamine)IBA 02/2006 - 01/2005
2	fumaric acid (sodium fumarate)IBA 07/2007 - 02/2006
2	LigandsIBA 07/2007 - 10/2002
2	SaltsIBA 07/2007 - 02/2006
2	Pharmaceutical PreparationsIBA 01/2006 - 03/2005
2	Formaldehyde (Formol)FDA Link 03/2005 - 06/2004
2	Baclofen FDA LinkGeneric 08/2003 - 12/2002
1	Phencyclidine (Angel Dust)IBA 09/2010
1	3- chloro- 4- fluorophenyl- (4- fluoro- 4- (((5- methylpyrimidin- 2- ylmethyl)amino)methyl)piperidin- 1- yl)methanoneIBA 09/2010
1	Naloxone (Narcan)FDA LinkGeneric 02/2006
1	Ketamine FDA LinkGeneric 01/2006
1	Imipramine (Janimine)FDA LinkGeneric 01/2006
1	mu Opioid Receptors (mu Opioid Receptor)IBA 01/2006
1	Gabapentin (Neurontin)FDA LinkGeneric 01/2006
1	Isoflurane FDA LinkGeneric 10/2005
1	Remifentanil (Ultiva)FDA Link 10/2005
1	Serotonin 5-HT1 Receptor AgonistsIBA 12/2004
1	tetralinIBA 06/2004
1	Nerve Growth Factors (Neurotrophins)IBA 04/2004
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 04/2004
1	3- (3- (N- (2- (3,4- dimethoxyphenyl)ethyl)- N- methylamino)propyloxy)- 5- phenyl- 1,2,4- thiadiazoleIBA 01/2004
1	Methadone (Dolophine)FDA LinkGeneric 08/2003
1	GABA-B Receptor AgonistsIBA 08/2003
1	donitriptanIBA 05/2003
1	Haloperidol (Haldol)FDA LinkGeneric 10/2002
1	3- chloro- 4- fluorophenyl- (4- fluoro- 4- (((5- methyl- 6- methylaminopyridin- 2- ylmethyl)amino)methyl)piperidin- 1- yl)methanoneIBA 10/2002
1	Antipsychotic Agents (Antipsychotics)IBA 10/2002
1	N- (2- (4- (2- methoxyphenyl)- 1- piperazinyl)ethyl)- N- (2- pyridinyl)cyclohexanecarboxamideIBA 10/2002
1	ipsapironeIBA 10/2002
1	dexefaroxanIBA 04/2002
1	NeurotoxinsIBA 04/2002

Therapy/Procedure

8	Analgesia 07/2007 - 12/2002
2	Therapeutics 02/2006 - 01/2006
1	Duration of Therapy 07/2007
1	Injections 02/2006